In the second step, CHARMM refinement, low energy structures generated by the first step are submitted to simulated annealing molecular dynamics with major tertiary contacts held in place. 第二步,CHARMM精制化,使用在第一步中所产生的低能量结构来模拟分子动力学。
Second is refinement step, in which spatial objects resulted from filter step are subjected to exacted computation. 第二步为细化步骤,对从第一步中筛选出的空间对象进行精确的空间运算操作。
Genetic Optimization to the Refinement Step of Spatial Join Processing 空间连接处理中提炼步骤的遗传优化
The housekeeping processing is usually performed to optimize the I/ O costs of spatial join refinement step. The problems in housekeeping phase have been shown NP-hard, and most methods solve them with high computation complexity. 内务处理是用来优化空间连接处理提炼步骤的I/O代价,属于NP-难的问题,现有求解方法复杂度太高。
After iterative refinement of each processing step, the optimal word-length and Q-Value of each intermediate results and coefficients are evolved. 通过对各个处理步骤迭代求精,从而引出各数据处理步骤中间运算结果及滤波系数的最佳字长及Q值。
Through an iteration of "resolution-check-refinement", the algorithm reduces ranges of constraint variables with range constraints and control constraints, and improves resolution precision of overflow expression step by step. 该方法通过一个求解一检查一改进的迭代过程,不断缩小约束变量在范围约束和控制约束下的取值范围,逐步提高溢出表达式的计算精度。